Molecular Imaging Reveals a High Degree of Cross-Seeding of Spontaneous Metastases in a Novel Mouse Model of Synchronous Bilateral Breast Cancer.

Shirley LiuNivin N NyströmJohn J KellyAmanda M HamiltonYanghao FuJohn A Ronald

Published in: Molecular imaging and biology (2021)

A high degree of metastatic cross-seeding of cancer cells derived from bilateral tumors may contribute to faster metastatic growth and intratumoral heterogeneity. We posit that our work will help understand treatment resistance and optimal planning of SBBC treatment.

Keyphrases

mouse model
squamous cell carcinoma
small cell lung cancer
single cell
combination therapy
young adults