Lipocalin-2 Deficiency Reduces Hepatic and Hippocampal Triggering Receptor Expressed on Myeloid Cells-2 Expressions in High-Fat Diet/Streptozotocin-Induced Diabetic Mice.
Hyun Joo ShinZhen JinHyeong Seok AnGyeongah ParkJong Youl LeeSo Jeong LeeHye Min JangEun Ae JeongKyung Eun KimJaewoong LeeDae Young YooGu Seob RohPublished in: Brain sciences (2022)
These findings indicate that LCN2 may promote hepatic inflammation and microglial activation via upregulation of TREM2 in diabetic mice.
Keyphrases
- high fat diet
- insulin resistance
- adipose tissue
- induced apoptosis
- diabetic rats
- oxidative stress
- cell cycle arrest
- high glucose
- signaling pathway
- inflammatory response
- dendritic cells
- bone marrow
- acute myeloid leukemia
- cell proliferation
- lipopolysaccharide induced
- neuropathic pain
- endoplasmic reticulum stress
- skeletal muscle
- endothelial cells
- type diabetes
- spinal cord
- immune response
- cerebral ischemia
- pi k akt
- long non coding rna
- smoking cessation