Coagulation profile of COVID-19 patients admitted to the ICU: An exploratory study.

Thiago Domingos CorrêaRicardo Luiz CordioliJoão Carlos Campos GuerraBruno Caldin da SilvaRoseny Dos Reis RodriguesGuilherme Martins de SouzaThais Dias MidegaNiklas Söderberg CamposBárbara Vieira CarneiroFlávia Nunes Dias CamposHélio Penna GuimarãesGustavo Faissol Janot de MatosValdir Fernandes de ArandaLeonardo José Rolim Ferraz

Published in: PloS one (2020)

COVID-19 patients have a pronounced hypercoagulability state, characterized by impaired endogenous anticoagulation and decreased fibrinolysis. The magnitude of coagulation abnormalities seems to correlate with the severity of organ dysfunction. The hypercoagulability state of COVID-19 patients was not only detected by ROTEM but it much more complex, where changes were observed on the fibrinolytic and endogenous anticoagulation system.

Keyphrases

sars cov
atrial fibrillation
venous thromboembolism
coronavirus disease
respiratory syndrome coronavirus
intensive care unit
mechanical ventilation