Antidiabetic Activity and Potential Mechanism of Amentoflavone in Diabetic Mice.

Chengfu SuChuanbin YangMan GongYingying KePeipei YuanXiaolan WangMin LiXiaoke ZhengWeisheng Feng

Published in: Molecules (Basel, Switzerland) (2019)

AME exerted anti-diabetic effects by regulating glucose and lipid metabolism, perhaps via anti-oxidant effects and activating the PI3K/Akt pathway. Our study provided novel insight into the role and underlying mechanisms of AME in diabetes.

Keyphrases

type diabetes
cardiovascular disease
signaling pathway
glycemic control
skeletal muscle