Efficacy and Safety of a Novel Therapeutic of Natural Origin (NTN) in Adult Patients with Lactose Intolerance: A Multicenter, Randomized, Crossover, Double-Blind, Placebo-Controlled Study.

Corina PopIoan SporeaJavier SantosNicolae TudorNicoleta Tiuca

Published in: Foods (Basel, Switzerland) (2022)

Subjective improvements in bloating, distension, and abdominal pain with NTN were supported by objective evidence of hydrogen production normalization. NTN appears to be a useful alternative to lactose avoidance or enzyme replacement in patients with lactose intolerance.

Keyphrases

double blind
placebo controlled
abdominal pain
clinical trial
phase iii
phase ii
study protocol
open label
physical activity