Mapping the human sperm proteome - novel insights into reproductive research.

Mika Alexia MiyazakiRaquel Lozano GuilharducciPaula IntasquiRicardo Pimenta Bertolla

Published in: Expert review of proteomics (2023)

Sperm function depends on protein abundance, conformation, and PTMs; understanding the sperm proteome may help to identify pathways essential to fertility, even making it possible to unravel the mechanisms involved in idiopathic infertility. In addition, proteomics evaluation offers knowledge regarding alterations that compromise the male reproductive potential.

Keyphrases

endothelial cells
healthcare
mass spectrometry
high resolution
protein protein
molecular dynamics simulations
metabolic syndrome
climate change
microbial community
risk assessment
high density
antibiotic resistance genes