Efficacy of safinamide as add-on therapy after subthalamic nucleus deep brain stimulation in Parkinson disease.

Mario Giorgio RizzoneFrancesca ManciniCarlo Alberto ArtusiRoberta BalestrinoSalvatore BonvegnaMargherita FabbriGabriele ImbalzanoElisa MontanaroAlberto RomagnoloMaurizio ZibettiLeonardo Lopiano

Published in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2022)

Safinamide seems to be an effective adjunctive treatment in PD patients treated with bilateral STN-DBS, leading to an improvement of motor complications, mood and pain.

Keyphrases

deep brain stimulation
parkinson disease
obsessive compulsive disorder
chronic pain
pain management
neuropathic pain
risk factors
sleep quality
case report
stem cells
physical activity
spinal cord
replacement therapy
mesenchymal stem cells
depressive symptoms