Intravenous immunoglobulin therapy enhances suppressive regulatory T cells and decreases innate lymphoid cells in children with immune thrombocytopenia.
Shih-Chung WangKuender D YangChing-Yuang LinAlex Yee-Chen HuangChien-Chou HsiaoMing-Tsan LinYi-Giien TsaiPublished in: Pediatric blood & cancer (2019)
Effective high-dose IVIG therapy for children with newly diagnosed ITP appears to result in the induction of Tregs, which suppresses ILC proliferation in vitro and is associated with platelet response.