Metformin Improves the Depression Symptoms of Women with Polycystic Ovary Syndrome in a Lifestyle Modification Program.
Fatimah AlHussainYazed Sulaiman H Al-RuthiaHazem Al-MandeelArwa BellahwalFadia AlharbiYasser S AlmogbelOriana AwwadRoua Dala'eenFawaz Abdullah AlharbiPublished in: Patient preference and adherence (2020)
Metformin may have a role in the management of depression symptoms among patients with PCOS; however, its potential antidepressant effect should be further examined in randomized double-blind placebo-controlled clinical trials.
Keyphrases
- placebo controlled
- double blind
- clinical trial
- sleep quality
- phase ii
- phase iii
- polycystic ovary syndrome
- depressive symptoms
- study protocol
- phase ii study
- open label
- cardiovascular disease
- major depressive disorder
- metabolic syndrome
- insulin resistance
- weight loss
- squamous cell carcinoma
- adipose tissue
- pregnant women
- skeletal muscle
- radiation therapy