Assessing mortality and safety of IV thrombolysis in ischemic stroke patients on direct oral anticoagulants (DOACs): A systematic review and meta-analysis.

Khadija AlamArsala Nadeem KhanAfia FatimaAbdul HaseebDuaa JaffarAbdullah MussaratMaryam AmirMuhammad Owais RanaHamid SaeedAbyaz Asmar

Published in: Clinical neurology and neurosurgery (2024)

The pooled analysis suggests that IVT is a safe management option for acute ischemic stroke in patients with DOAC intake before symptom onset without an increased risk of serious adverse events.

Keyphrases

direct oral anticoagulants
acute ischemic stroke
venous thromboembolism
atrial fibrillation
end stage renal disease
ejection fraction
newly diagnosed
pulmonary embolism
prognostic factors
peritoneal dialysis
type diabetes
patient reported
body mass index