Mutation of mltG increases peptidoglycan fragment release, cell size, and antibiotic susceptibility in Neisseria gonorrhoeae .
Tiffany N Harris-JonesKrizia M Pérez MedinaKathleen T HackettMelanie A SchaveAmy K KlimowiczRyan E SchaubJoseph P DillardPublished in: Journal of bacteriology (2023)
mutants suggest that an antimicrobial drug inhibiting MltG would be useful in combination therapy to restore the sensitivity of the bacteria to cell wall targeting antibiotics to which the bacteria are currently resistant.