Frequency of HLA-DQ, susceptibility genotypes for celiac disease, in Brazilian newborns.
Fernanda C AlmeidaLenora GandolfiKarina N CostaMarilucia R A PicançoLucas M AlmeidaYanna K M NóbregaRiccardo PratesiClaudia B PratesiNicole SelleskiPublished in: Molecular genetics & genomic medicine (2018)
43.7% of the analyzed individual tested positive for at least one of the CD predisposing HLA-DQ genotypes in our group of Brazilian NB. The highest frequency was found for DQ2.5 positive subjects (17.6%) followed by DQ8 (11.3%); DQ2.2 (10.3%); DQ8 and DQ2.2 (3.0%); DQ2.5 and DQ8 (1.5%). We found no positive sample for DQ2.5 associated with DQ2.2.