Role of IL-6 and STAT3 signaling in dihydropyridine-induced gingival overgrowth fibroblasts.
Sao-Lun LuChiung-Fang HuangChuan-Li LiHsein-Kun LuSam Li-Sheng ChenPublished in: Oral diseases (2020)
Gingival inflammation (e.g., IL-1β) and taking dihydropyridine (e.g., Nif) may additively stimulate Col overproduction through the IL-6-STAT3-Colα1(I) cascade in DIGO cells. IL-6-STAT3 signaling may be considered a target for the control of DIGO.