Meta-analysis: analysis of mechanistic pathways in the treatment of non-alcoholic steatohepatitis. Evidence from a Bayesian network meta-analysis.

Cheng-Han Ng Mark Dhinesh MuthiahJieling XiaoYip Han ChinGrace LimWen Hui LimPhoebe TayDarren Jun Hao TanJie Ning YongXin-Hui PanJeffery Wei Heng KohNicholas ChewNicholas Li-Xun SynEunice TanDaniel Q HuangMohammad Shadab SiddiquiStephen Caldwell Arun J Sanyal Mazen Noureddin

Published in: Alimentary pharmacology & therapeutics (2022)

This network analysis demonstrates the relative superiority of drugs modulating energy pathways and bile acids in NASH treatment. This guides the development and selection of drugs for combination therapies.

Keyphrases

systematic review
network analysis
meta analyses
signaling pathway
combination therapy
case control
drug induced
liver fibrosis