miR-27b inhibits fibroblast activation via targeting TGFβ signaling pathway.
Xiangming ZengChaoqun HuangLakmini SenavirathnaPengcheng WangLin Liu
Published in: BMC cell biology (2017)
Our results suggest that miR-27b is an anti-fibrotic microRNA that inhibits fibroblast activation by targeting TGFβ receptor 1 and SMAD2. This discovery may provide new targets for therapeutic interventions of idiopathic pulmonary fibrosis.