In vitro effects of Apixaban on 5 different cancer cell lines.

Luigina GuastiAlessandro SquizzatoPaola MorettoDavide VigettiWalter AgenoFrancesco DentaliAndrea M MarescaLeonardo CampiottiAnna M GrandiAlberto Passi

Published in: PloS one (2017)

Our data suggest that high-dose Apixaban may be able to interfere with cancer cell in vitro, reducing proliferation and increasing cancer cell mortality through apoptosis in several cancer cell lines.

Keyphrases

papillary thyroid
high dose
venous thromboembolism
squamous cell
atrial fibrillation
low dose
oxidative stress
cardiovascular events
signaling pathway
electronic health record
squamous cell carcinoma
lymph node metastasis
risk factors
type diabetes
big data
stem cell transplantation
cell proliferation
deep learning