Prognostic utility of circulating tumor DNA methylation analysis in stage IV colorectal cancer.

Hirotaka MomoseKiichi SugimotoTakahiro IrieSachio NomuraHisashi RoShun IshiyamaMakoto TakahashiThomas PisanicKazuhiro Sakamoto

Published in: Journal of surgical oncology (2024)

The current study showed the usefulness of ctDNA methylation analysis for predicting the possibility of curative resection and long-term outcomes after resection in Stage IV CRC. A future prospective study is needed to obtain more conclusive results.

Keyphrases

dna methylation
circulating tumor
genome wide
gene expression
circulating tumor cells
copy number
data analysis