The circular RNA circSPARC enhances the migration and proliferation of colorectal cancer by regulating the JAK/STAT pathway.
Jiaqi WangYi ZhangHu SongHang YinTao JiangYixin XuLianyu LiuHongyu WangHong GaoRenhao WangJun SongPublished in: Molecular cancer (2021)
These findings suggest that circSPARC might serve as a potential diagnostic and prognostic biomarker and a therapeutic target for CRC treatment by regulating JAK2/STAT3 pathway.