Multiparametric chemical exchange saturation transfer MRI detects metabolic changes in breast cancer following immunotherapy.

Emily HoffmannDaniel SchacheCarsten HöltkeJens SoltwischStephan NilandTobias KrählingKlaus BerganderMartin GrewerChristiane GeyerLinda GroenewegJohannes A EbleThomas VoglJohannes RothWalter HeindelBastian MausAnne HelfenCornelius FaberMoritz WildgruberMirjam GerwingVerena Hoerr

Published in: Journal of translational medicine (2023)

Multiparametric CEST-MRI enables non-invasive assessment of metabolic signatures of the TME, allowing both for estimation of the degree of tumor malignancy and for assessment of early response to immune checkpoint inhibition.

Keyphrases

contrast enhanced
magnetic resonance imaging
diffusion weighted imaging
computed tomography
magnetic resonance
gene expression
breast cancer risk