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Multiparametric chemical exchange saturation transfer MRI detects metabolic changes in breast cancer following immunotherapy.

Emily HoffmannDaniel SchacheCarsten HöltkeJens SoltwischStephan NilandTobias KrählingKlaus BerganderMartin GrewerChristiane GeyerLinda GroenewegJohannes A EbleThomas VoglJohannes RothWalter HeindelBastian MausAnne HelfenCornelius FaberMoritz WildgruberMirjam GerwingVerena Hoerr
Published in: Journal of translational medicine (2023)
Multiparametric CEST-MRI enables non-invasive assessment of metabolic signatures of the TME, allowing both for estimation of the degree of tumor malignancy and for assessment of early response to immune checkpoint inhibition.
Keyphrases
  • contrast enhanced
  • magnetic resonance imaging
  • diffusion weighted imaging
  • computed tomography
  • magnetic resonance
  • gene expression
  • breast cancer risk