Differentiation of hypervirulent and classical Klebsiella pneumoniae with acquired drug resistance.

Thomas A RussoCassandra L AlvaradoConnor J DaviesZachary J DrayerUlrike Carlino-MacDonaldAlan HutsonTing L LuoMelissa J MartinBrendan W CoreyKara A MoserJ Kamile RasheedAlison S Laufer Halpin Patrick T Mc Gann Francois Lebreton

Published in: mBio (2024)

was most accurate (94%); the presence of ≥4 of these biomarkers was most sensitive (100%). Accurately identifying hvKp is vital for surveillance and research, and the availability of biomarker data could alert the clinician that hvKp is a consideration, which, in turn, would assist in optimizing patient care.

Keyphrases

klebsiella pneumoniae
multidrug resistant
escherichia coli
electronic health record
public health
clinical decision support
fluorescent probe
big data
living cells
sensitive detection
high resolution
machine learning
data analysis
artificial intelligence