Cranial Ultrasound Findings in Infants with Congenital Cytomegalovirus Infection in a Universal Newborn Screening Study in Minnesota.
Rebecca M KrucErin A OsterholmTara HolmIgor NestrasilTatiana M LanzieriMark R SchleissPublished in: Journal of the Pediatric Infectious Diseases Society (2024)
Among infants with cCMV identified in a universal screening study, the majority had a normal cUS. CNS disease-defining abnormalities were present in 7%, while 24% had findings of uncertain significance. We propose that many cUS findings are incidental, and not diagnostic of symptomatic cCMV infection. Although insufficient to define symptomatic disease, incidental findings were more common in infants with other manifestations of cCMV infection.
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