Vasopressin augments TNBS-induced colitis through enteric neuronal V1a receptor-mediated COX-2-dependent prostaglandin release from mast cells in mice.

Dandan DouLixin ChenHong DiZhuoran SongShirui LiXinjie BuQing DaiShuai WangJing Xin LiXiaolong ZhuHaiyan Jing

Published in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2018)

VP-V1a receptor played the proinflammatory role in TNBS-induced colitis by promoting COX-2-dependent prostaglandin release from mucosal mast cells, which was mediated by the cholinergic pathway.

Keyphrases

type diabetes
adipose tissue
skeletal muscle
cerebral ischemia
brain injury