Subfamily-specific differential contribution of individual monomers and the tether sequence to mouse L1 promoter activity.
Lingqi KongKarabi SahaYuchi HuJada N TschetterChase E HabbenLeanne S WhitmoreChangfeng YaoXijin GePing YeSimon J NewkirkWenfeng AnPublished in: Mobile DNA (2022)
The laboratory mouse is an important mammalian model system for human diseases as well as L1 biology. Our study extends previous findings and represents an important step toward a better understanding of the molecular mechanism controlling mouse L1 transcription as well as L1's impact on development and disease.