Risk Factors for Colonization With Extended-Spectrum Cephalosporin-Resistant and Carbapenem-Resistant Enterobacterales Among Hospitalized Patients in Kenya: An Antibiotic Resistance in Communities and Hospitals (ARCH) Study.
Sylvia OmuloTeresa ItaRobert MugohCharchil AyodoUlzii LuvsansharavSusan BollingerAshley StyczynskiBrooke M RamayMark A CaudellGuy H PalmerSamuel KariukiDouglas R CallRachel M SmithPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2023)
While CRE colonization was strongly associated with ceftriaxone use and duration of antibiotic use, the odds of ESCrE colonization increased with exposure to the hospital setting and invasive medical devices, which may reflect nosocomial transmission. These data suggest several areas where hospitals can intervene to prevent colonization among hospitalized patients, both through robust infection prevention and control practices and antibiotic stewardship programs.