Orbital Complication in the Setting of Cocaine Use: A Case Report and Review of Literature.
Calvin W WongMichael Y ZhaoJohn J McDermottDebora H LeeTimothy J McCulleyYing ChenPublished in: Ophthalmic plastic and reconstructive surgery (2024)
Orbital cellulitis is a common ophthalmologic consultation and has numerous risk factors; however, one that is seldomly encountered is chronic cocaine use. We describe a case of a 63-year-old man with a history of HIV and cocaine use who presented with OD pain, proptosis, and blurred vision. CT imaging revealed extensive erosions throughout the nasal septum, bilateral turbinates, ethmoid sinuses, and loss of the right medial orbital wall. The patient was treated empirically with broad-spectrum antibiotics, and a nasal biopsy and culture grew Staphylococcus aureus. After treatment with IV antibiotics, the patient's visual acuity returned to baseline with resolution of extraocular motility limitations. Although nasal erosions are a well-described sequela of cocaine use, full-thickness osseous defects of the orbital wall are rare and represent late-stage complications of cocaine-induced destructive midline lesions. Orbital cellulitis is a very rare complication in the setting of cocaine-induced destructive midline lesions. Clinicians should be aware of the link between cocaine use, rhino-orbital abnormalities, and orbital cellulitis.
Keyphrases
- risk factors
- staphylococcus aureus
- prefrontal cortex
- case report
- palliative care
- high glucose
- diabetic rats
- chronic rhinosinusitis
- high resolution
- drug induced
- hepatitis c virus
- magnetic resonance
- hiv positive
- hiv infected
- oxidative stress
- single cell
- spinal cord injury
- optical coherence tomography
- hiv aids
- escherichia coli
- endothelial cells
- human immunodeficiency virus
- cystic fibrosis
- men who have sex with men
- pet ct