Severe Acute Respiratory Syndrome Coronavirus 2 Adaptive Immunity in Nursing Home Residents Following a Third Dose of the Comirnaty Coronavirus Disease 2019 Vaccine.

Estela GiménezEliseo AlbertJoao ZulaicaIgnacio TorresLuciana RusuAlicia Rodríguez MorenoJavier S BurgosSalvador PeiróDolores SalasHermelinda VanaclochaRamón LimónMaría Jesús AlcarazJosé Sánchez-PayáJavier Díez-DomingoIñaki ComasFernando Gonzáles-CandelasRon GellerDavid Navarronull null

Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2022)

A third Comirnaty vaccine dose increased severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor-binding domain antibody levels (median, 93-fold) and neutralizing antibody titers against Wuhan-Hu-1 (median, 57-fold), Beta (me 22-fold), Delta, (median, 43-fold), and Omicron (median, 8-fold) variants, but had less impact on S-reactive T-cell immunity in nursing home residents.

Keyphrases

respiratory syndrome coronavirus
coronavirus disease
sars cov
copy number
gene expression
zika virus
binding protein