Ceftriaxone Calcium Crystals Induce Acute Kidney Injury by NLRP3-Mediated Inflammation and Oxidative Stress Injury.

Zhang YifanNing BenxiangXu ZhengXu LuweiLiuhua ZhouGe YuzhengRuipeng Jia

Published in: Oxidative medicine and cellular longevity (2020)

Notably, we found that ceftriaxone-induced urolithiasis was associated with a high risk of AKI and NLRP3-mediated inflammasome and oxidative stress injury were of major importance in the pathogenesis.

Keyphrases

oxidative stress
diabetic rats
dna damage
ischemia reperfusion injury
drug induced
induced apoptosis
liver failure
acute kidney injury
high glucose
nlrp inflammasome
respiratory failure
room temperature
endoplasmic reticulum stress
acute respiratory distress syndrome