Diagnostic relevance of IgE sensitization profiles to eight recombinant Phleum pratense molecules.
F CiprianiC MastrorilliS TripodiG RicciS PernaV PanettaRiccardo AseroA DondiA BianchiN MaielloM Miraglia Del GiudiceT FredianiF MacrìS LucarelliI Dello IaconoM F PatriaE VarinD PeroniL ChiniV MoscheseR BernardiniG PingitoreU PelosiM ToscaF ParavatiI SfikaA Di Rienzo BusincoC Povesi DascolaP ComberiatiS FredianiC LambiaseM C VergaD FaggianM PlebaniM CalvaniC CaffarelliPaolo Maria Matricardinull nullPublished in: Allergy (2017)
In a large pediatric population, the complexity of IgE sensitization profiles against P. pratense molecules is related to high atopic features although useless for predicting the clinical severity. The detection of serum IgE to Phl p 1, Phl p 7, and Phl p 12 can be used as clinical biomarkers of SARg and comorbidities. Further studies in different areas are required to test the impact of different IgE molecular profiles on AIT response.
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