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CpG location and methylation level are crucial factors for the early detection of oral squamous cell carcinoma in brushing samples using bisulfite sequencing of a 13-gene panel.

Luca MorandiDavide GissiAchille TarsitanoSofia AsioliAndrea GabusiClaudio MarchettiLucio MontebugnoliMaria Pia Foschini
Published in: Clinical epigenetics (2017)
Our data highlight the importance of CpG location and correct estimation of DNA methylation level for highly accurate early diagnosis of OSCC.
Keyphrases
  • dna methylation
  • genome wide
  • copy number
  • gene expression
  • electronic health record
  • single cell
  • big data
  • high resolution
  • genome wide identification
  • deep learning