The impact of prevention-effective PrEP use on HIV incidence: a mathematical modelling study.
D Allen RobertsDaniel BridenbeckerJessica E HabererRuanne V BarnabasAdam AkullianPublished in: Journal of the International AIDS Society (2022)
Modelling PrEP use based on risk groups resulted in a sharp trade-off between PrEP efficiency and impact, whereas PrEP use predicated on partnerships resulted in much higher efficiency for widespread PrEP availability. Model estimates of PrEP impact and cost-effectiveness in generalized epidemics are strongly influenced by assumptions about how PrEP use aligns with individual-level HIV exposure heterogeneity.