A pilot study: intraoperative 16S rRNA sequencing versus culture in predicting colorectal incisional surgical site infection.
Veral VishnoiEmily C HoedtTiffany GouldGeorgia M CarrollRosemary CarrollNatalie LottPeter PockneyStephen R SmithSimon KeelyPublished in: ANZ journal of surgery (2023)
16S rRNA amplicon sequencing has demonstrated a potential difference in the intraoperative microbial profile of those that develop an infection. These findings require validation through powered experiments to determine the overall clinical significance.