Transitory outward pupillary curling in a case of HSV associated acute anterior uveitis: a hitherto unreported sign.
Samendra KarkhurDeepak SoniBhavana SharmaPublished in: BMJ case reports (2020)
We report a case of herpes simplex virus (HSV) associated acute anterior uveitis in otherwise healthy 38-year-old man with an unusual finding of outward pupillary margin curling. At presentation visual acuity was 20/60 in right eye (OD) and 20/20 in left eye (OS). Intraocular pressure was 44 and 18 mm Hg in OD and OS respectively. OD revealed diffuse conjunctival congestion, stromal oedema, pigmented keratic precipitates, cells grade 3+ and flare 2+ on slit-lamp examination and diminished corneal sensations. OS was unremarkable. There was a history of three similar episodes in last 1 year. Aetiology of this recurrent acute anterior uveitis was confirmed to be HSV via DNA-PCR assay of aqueous fluid. This hitherto unreported sign associated with viral hypertensive uveitis was transitory in nature and reversible with control of anterior chamber inflammation, without leaving any permanent damage. Topical steroids and antiglaucoma were stopped, while antiviral therapy was continued for 3 months.
Keyphrases
- herpes simplex virus
- juvenile idiopathic arthritis
- liver failure
- ankylosing spondylitis
- respiratory failure
- oxidative stress
- aortic dissection
- drug induced
- blood pressure
- induced apoptosis
- sars cov
- bone marrow
- wound healing
- mesenchymal stem cells
- circulating tumor
- low grade
- case report
- cell death
- cell proliferation
- mechanical ventilation
- loop mediated isothermal amplification
- acute respiratory distress syndrome
- replacement therapy
- real time pcr