Comparative effectiveness of angiotensin-converting enzyme inhibitors versus angiotensin II receptor blockers for major renal outcomes in patients with diabetes: A 15-year cohort study.

Hon-Yen WuChiao-Ling PengPei-Chun ChenChih-Kang ChiangChee-Jen ChangJenq-Wen HuangYu-Sen PengYu-Kang TuTzong-Shinn ChuKuan-Yu HungKuo-Liong Chien

Published in: PloS one (2017)

Our analyses show similar effects of ACEIs and ARBs in patients with diabetes. However, ACEIs might provide additional renoprotective effects among patients who have cardiovascular disease or chronic kidney disease.

Keyphrases

angiotensin converting enzyme
angiotensin ii
chronic kidney disease
cardiovascular disease
vascular smooth muscle cells
end stage renal disease
type diabetes
metabolic syndrome
skeletal muscle
adipose tissue
insulin resistance