Temporal analysis of bovine pestivirus diversity in Brazil.
Ana Cristina Sbaraini MosenaJonas Michel WolfWillian Pinto PaimLetícia Ferreira BaumbachMariana Soares da SilvaSimone SilveiraJuliana do Canto OlegárioRenata da Fontoura BudaszewskiMatheus Nunes WeberCláudio Wageck CanalPublished in: Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] (2022)
In this study, phylogenetic and evolutionary analyses of cattle pestiviruses (BVDV-1, 2 and HoBiPeV) originating in Brazil were used to investigate the temporal diversification of subgenotypes in the country. Inferred dated phylogeny and time of the most recent common ancestor (tMRCA) demonstrated that some BVDV subgenotypes (1a, 1b, 1d, 1e, and 2b) and HoBi-like sequences clustered according to the region in which they were collected and that the diversification of subgenotypes appears to have occurred around the introduction of first Bos taurus and then Bos indicus, followed by expansion to form the adapted Brazilian breeds. The present results help to elucidate the temporal facts that led to diversification of ruminant pestiviruses in cattle in Brazil.