Pharmacokinetic Basis of the Hydroxychloroquine Response in COVID-19: Implications for Therapy and Prevention.

Published in: European journal of drug metabolism and pharmacokinetics (2020)

These considerations may not only be applied to chloroquine/hydroxychloroquine but may have more general implications for development of anti-COVID-19 combination therapies and prevention strategies through an increased death rate of the infected cells.

Keyphrases

coronavirus disease
sars cov
induced apoptosis
cell cycle arrest
respiratory syndrome coronavirus
endoplasmic reticulum stress
signaling pathway
cell death
mesenchymal stem cells
pi k akt