Sex-biased gene regulation varies across human populations as a result of adaptive evolution.
Adam Z ReynoldsSara D NiedbalskiPublished in: American journal of biological anthropology (2023)
These results indicate that sex-biased gene expression is more flexible than previously thought and is not generally shared among human populations. Instead, molecular phenotypes associated with sex depend on complex interactions between population-specific molecular evolution and physiological responses to contemporary socioecologies.