Genetics of neuropsychiatric symptoms in patients with Alzheimer's disease: A 1-year follow-up study.

Mei-Feng HuangWei-Ju LeeYi-Chun YehYi-Chu LiaoShuu-Jiun WangYi-Hsin YangCheng-Sheng Chen Jong-Ling Fuh

Published in: Psychiatry and clinical neurosciences (2020)

Risk genes of AD, which are also associated with NPS, are APOE ε4 for psychosis, CD33 and EPHA1 for mood symptoms, and SORL1 for frontal symptoms. The association between CD33 and mood symptoms is dynamic and could change over 1 year; however, the results should be interpreted with caution because corrections for multiple comparisons were not performed.

Keyphrases

sleep quality
bipolar disorder
genome wide
gene expression
high fat diet
working memory
depressive symptoms
dna methylation
nk cells
skeletal muscle
genome wide identification