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Extracellular Vesicles from Adipose Tissue-Derived Stromal Cells Stimulate Angiogenesis in a Scaffold-Dependent Fashion.

V E GetovaE Orozco-GarcíaS PalmersG KrenningR Narvaez-SanchezMartim Conrad Harmsen
Published in: Tissue engineering and regenerative medicine (2024)
Our study revealed that ASC-EVs augment in vitro and ex vivo vascularisation, likely due to the enriched pro-angiogenic miRNAs in EVs, particularly miR-1290. Our results show promise for regenerative and revascularisation therapies based on ASC-EV-loaded ECM hydrogels.
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