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Response to pegylated interferon in a COVID-19-positive elderly woman with primary myelofibrosis treated with ruxolitinib.

Arthur E FrankelRenuka ReddyKayla R DeSuzaKhaled DeebAaron F CarlinDavey SmithYushuang XieEknath NaikRichard T SilverHans Carl Hasselbalch
Published in: Clinical case reports (2021)
An 83-year-old female had asymptomatic SARS-CoV-2 infection while taking ruxolitinib. She remained RT-PCR positive for viral RNA for >120 days, and Pegylated interferon for 4 weeks led to viral RNA clearance. The observations support combination therapy of ruxolitinib + interferon for COVID-19.
Keyphrases
  • sars cov
  • combination therapy
  • coronavirus disease
  • respiratory syndrome coronavirus
  • dendritic cells
  • nucleic acid
  • middle aged
  • case report
  • recombinant human