Epileptogenic networks in nodular heterotopia: A stereoelectroencephalography study.
Francesca PizzoNicolas RoehriHelene CatenoixSamuel MedinaAileen McGonigalBernard GiusianoRomain CarronDidier ScavardaKarine OstrowskyAnne LepineSébastien BoulogneJulia SchollyEdouard HirschSylvain RheimsChristian-George BénarFabrice BartolomeiPublished in: Epilepsia (2017)
This is the first quantitative SEEG study providing insight into the mechanisms generating seizures in nodular heterotopia. We demonstrate that both the heterotopic lesion and particularly the normotopic cortex are involved in the epileptogenic network. This could open new perspectives on multitarget treatments, other than resective surgery, aimed at modifying the epileptic network.