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A Novel Multiobject Tracking Approach in the Presence of Collision and Division.

Mingli LuBenlian XuAndong ShengZhengqiang JiangLiping WangPeiyi ZhuJian Shi
Published in: Computational and mathematical methods in medicine (2015)
This paper aims to develop a general framework for accurately tracking and quantitatively characterizing multiple cells (objects) when collision and division between cells arise. Through introducing three types of interaction events among cells, namely, independence, collision, and division, the corresponding dynamic models are defined and an augmented interacting multiple model particle filter tracking algorithm is first proposed for spatially adjacent cells with varying size. In addition, to reduce the ambiguity of correspondence between frames, both the estimated cell dynamic parameters and cell size are further utilized to identify cells of interest. The experiments have been conducted on two real cell image sequences characterized with cells collision, division, or number variation, and the resulting dynamic parameters such as instant velocity, turn rate were obtained and analyzed.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • endoplasmic reticulum stress
  • machine learning
  • cell death
  • cell therapy
  • cell proliferation
  • bone marrow
  • quantum dots