Impact of five-tiered Gleason grade groups on prognostic prediction in clinical stage T3 prostate cancer undergoing high-dose-rate brachytherapy.

Hideyasu TsumuraHiromichi IshiyamaKen-Ichi TabataHiroki KatsumataMomoko KobayashiMasaomi IkedaShinji KurosakaTetsuo FujitaMasashi KitanoTakefumi SatohNobuyuki YanagisawaKazushige HayakawaMasatsugu Iwamura

Published in: The Prostate (2017)

Stage T3a patients with grade groups 4/5 and stage T3b with grade group 4 had fairly low PCSM risk. Approximately one of four patients among stage T3b patients with grade group 5 showed PCSM after combined HDR-BT and EBRT with long-term ADT. Stage T3b patients with grade group 5 may have a greater risk for PCSM.

Keyphrases

prostate cancer
high dose
radical prostatectomy
ejection fraction
newly diagnosed
low dose
squamous cell carcinoma
prognostic factors
chronic kidney disease
locally advanced
rectal cancer
breast cancer risk