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Hsa_circ_0072309 enhances autophagy and TMZ sensitivity in glioblastoma.

Fanen YuanSi ZhangQian SunLiguo YeYang XuZhou XuGang DengShenqi ZhangBao-Hui LiuQian-Xue Chen
Published in: CNS neuroscience & therapeutics (2022)
This study revealed a function of hsa_circ_0072309 promoting autophagy by p53 signaling pathway and enhancing TMZ sensitivity. These findings demonstrated that hsa_circ_0072309 may be a potential and promising target in designing the treatment strategy for GBM.
Keyphrases
  • signaling pathway
  • cell death
  • endoplasmic reticulum stress
  • pi k akt
  • oxidative stress
  • induced apoptosis
  • single cell
  • human health
  • climate change
  • replacement therapy
  • human serum albumin