A case of juvenile eosinophilic cholangitis: Rapid peripheral blood hypereosinophilia after admission leading to diagnosis.
Shusaku FukatsuKatsuya KitamuraYasutsugu AsaiKazumasa NagaiMiho KikuchiKyoko AsanoKenichi TadokoroFumito YamanishiYusuke TomitaMasakazu AbeTakuya WadaYubu MatsueDaisuke NutaharaJunichi TairaHironori NakamuraTakao ItoiPublished in: JGH open : an open access journal of gastroenterology and hepatology (2020)
A 15-year-old boy was referred to our hospital with elevated hepatobiliary enzyme levels and jaundice. Magnetic resonance cholangiopancreatography performed at the previous medical facility revealed a stricture of the intrahepatic and extrahepatic bile duct. Computed tomography showed dilatation and wall thickness of the intrahepatic bile ducts. Primary sclerosing cholangitis or cholangiocarcinoma was suspected. Endoscopic retrograde cholangiopancreatography (ERCP) showed stricture in the intrahepatic and extrahepatic bile duct. On admission, the eosinophil count in the peripheral blood was normal; however, rapid hypereosinophilia in the peripheral blood was observed after admission, leading us to suspect eosinophilic cholangitis (EC). A bile duct biopsy showed inflammatory cells and eosinophil infiltration during a second ERCP. The patient was diagnosed with EC based on histopathology.
Keyphrases
- peripheral blood
- magnetic resonance
- emergency department
- computed tomography
- ultrasound guided
- chronic rhinosinusitis
- induced apoptosis
- healthcare
- endoscopic submucosal dissection
- ulcerative colitis
- loop mediated isothermal amplification
- cell cycle arrest
- contrast enhanced
- oxidative stress
- magnetic resonance imaging
- case report
- positron emission tomography
- single cell
- optical coherence tomography
- fine needle aspiration
- endoplasmic reticulum stress
- cell death
- cell proliferation
- signaling pathway
- adverse drug
- image quality
- quantum dots