Dexamethasone and Training-Induced Cardiac Remodeling Improve Cardiac Function and Arterial Pressure in Spontaneously Hypertensive Rats.
Francine DuchatschLidieli P TardelliNaiara A HerreraThalles F R RuizCarlos A VicentiniKatashi OkoshiCarlos F SantosSandra Lia do AmaralPublished in: Journal of cardiovascular pharmacology and therapeutics (2020)
In conclusion, this study is unique to indicate that low-dose of DEX treatment does not exacerbate arterial pressure in SHR and, when associated with training, it improves LV systolic and diastolic function, which may be due to LV angiogenesis and reduction of wall collagen deposition area.