Glomerular filtration rate in critically ill neonates and children: creatinine-based estimations versus iohexol-based measurements.
Nori J L SmeetsEsther M M TeunissenKim van der VeldenMaurice J P van der BurghDemi E LindersElodie TeesselinkDirk-Jan A R MoesCamilla TøndelRob Ter HeineArno van HeijstMichiel F SchreuderSaskia N de WildtPublished in: Pediatric nephrology (Berlin, Germany) (2022)
Iohexol-based AKI prevalence was higher and ARC prevalence lower compared to standard SCr-based eGFR methods. Age- and sex-dependent equations for eGFR (eGFR-Smeets for neonates and eGFR-Pierce for children) best approached measured GFR and should preferably be used to optimize diagnosis of AKI and ARC in this population. A higher resolution version of the Graphical abstract is available as Supplementary information.