Polymorphisms of the renin-angiotensin system are not associated with overweight and obesity in a general adult population.

Deborah de Farias LelisAlexandre Costa PereiraJose Eduardo Krieger Jose Geraldo Mill Sérgio Henrique Sousa Santos Marcelo Perim Baldo

Published in: Archives of endocrinology and metabolism (2019)

We were not able to find any associations between BMI and WC (overweight/obesity) and ACE and AGT polymorphisms, indicating that the RAS system might not be involved in overweight and obesity, at least based on genetic backgrounds. However, further studies must measure RAS components to elucidate this question.

Keyphrases

weight gain
weight loss
wild type
body mass index
metabolic syndrome
insulin resistance
type diabetes
physical activity
genome wide
angiotensin ii
copy number
case control
gene expression