Predictive Ability of Visit-to-Visit Variability of HbA1c Measurements for the Development of Diabetic Kidney Disease: A Retrospective Longitudinal Observational Study.
Yunyi YanNozomi KondoKentaro OnikiHiroshi WatanabeTadashi ImafukuYuki SakamotoTakuro ShigakiAkari MaruyamaHitomi NakazawaTetsuya KanekoAyami MoritaAkira YoshidaHitoshi MaedaToru MaruyamaHideaki JinnouchiJunji SaruwatariPublished in: Journal of diabetes research (2022)
Visit-to-visit variability of HbA1c was an independent risk factor of microalbuminuria in association with oxidative stress among type 2 diabetes mellitus patients. HbA1c-AUC, a novel index of HbA1c variability, may be a potent prognostic indicator in predicting the risk of microalbuminuria.