Chitinase-like protein YKL-40 correlates with inflammatory phenotypes, anti-asthma responsiveness and future exacerbations.
Lei LiuXin ZhangYing LiuLi ZhangJing ZhengJi WangPhilip M HansbroLei WangGang WangAlan Chen-Yu HsuPublished in: Respiratory research (2019)
These studies show that YKL-40 is a non-type 2 inflammatory signature for NEA, which could predict responsiveness or insensitivity to anti-asthma medications and more exacerbations. Further studies are needed to assess whether monitoring YKL-40 levels could provide potential implications for clinical relevance.