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Suppression of myeloid PFKFB3-driven glycolysis protects mice from choroidal neovascularization.

Zhiping LiuXiaoxiao MaoQiuhua YangXiaoyu ZhangJiean XuQian MaYaqi ZhouQingen DaYongfeng CaiAnu SopeyinZheng DongMei HongRuth B CaldwellAkrit SodhiYuqing Huo
Published in: British journal of pharmacology (2022)
Modulation of PFKFB3-mediated macrophage glycolysis and activation is a promising strategy for the treatment of nAMD.
Keyphrases
  • dendritic cells
  • adipose tissue
  • diabetic retinopathy
  • high fat diet induced
  • type diabetes
  • age related macular degeneration
  • optic nerve